מחקרים ופרסומים


Real-world effectiveness of sucroferric oxyhydroxide in patients on chronic hemodialysis: A retrospective analysis of pharmacy data
Article

Real-world effectiveness of sucroferric oxyhydroxide in patients on chronic hemodialysis: A retrospective analysis of pharmacy data

Abstract AIMS: Hyperphosphatemia has been associated with an increased risk of mortality in patients with end-stage renal disease. We

Iron-related parameters in dialysis patients treated with sucroferric oxyhydroxide
Article

Iron-related parameters in dialysis patients treated with sucroferric oxyhydroxide

Abstract Background Sucroferric oxyhydroxide is a non-calcium, iron-based phosphate binder indicated for the treatment of hyperphosphataemia in adult dialysis

הטיפול ב- Sucroferric (וולפורו) אינו נחות מ-sevelamer (רנוולה) בשליטה ברמות הזרחן במטופלים בדיאליזה פריטוניאלית וזאת בלווי נטל תרופתי קטן יותר והיענות גבוהה יותר (Nephrol Dial Transplant )
מחקרים ופרסומים

הטיפול ב- Sucroferric (וולפורו) אינו נחות מ-sevelamer (רנוולה) בשליטה ברמות הזרחן במטופלים בדיאליזה פריטוניאלית וזאת בלווי נטל תרופתי קטן יותר והיענות גבוהה יותר (Nephrol Dial Transplant )

ע"פ מחקר חדש מה-Nephrol Dial Transplant הטיפול ב-Sucroferric oxyhydroxide (וולפורו) אינו נחות מהטיפול ב-sevelamer(רנוולה) לשליטה ברמות הזרחן במטופלים בדיאליזה פריטוניאלית (PD)

Pharmacodynamic Effects of Sucroferric Oxyhydroxide and Sevelamer Carbonate on Vitamin D Receptor Agonist Bioactivity in Dialysis Patients
Article

Pharmacodynamic Effects of Sucroferric Oxyhydroxide and Sevelamer Carbonate on Vitamin D Receptor Agonist Bioactivity in Dialysis Patients

Abstract BACKGROUND: Many patients with chronic kidney disease are prescribed vitamin D receptor agonists (VDRAs) for the management of secondary hyperparathyroidism. Oral phosphate binders may

Phosphate binders in chronic kidney disease: a systematic review of recent data
Article

Phosphate binders in chronic kidney disease: a systematic review of recent data

Abstract Hyperphosphatemia is common in chronic kidney disease (CKD) and is treated by dietary measures, dialysis techniques and/or phosphatebinders. For the present

Improvement of mineral and bone metabolism markers is associated with better survival in haemodialysis patients: the COSMOS study
Article

Improvement of mineral and bone metabolism markers is associated with better survival in haemodialysis patients: the COSMOS study

Abstract BACKGROUND: Abnormalities in serum phosphorus, calcium and parathyroid hormone (PTH) have been associated with poor survival in haemodialysis patients. This COSMOS (Current management Of Secondary hyperparathyroidism:

Long-term effects of the iron-based phosphate binder, sucroferric oxyhydroxide, in dialysis patients
Article

Long-term effects of the iron-based phosphate binder, sucroferric oxyhydroxide, in dialysis patients

Abstract Background Hyperphosphatemia necessitates the use of phosphate binders in most dialysis patients. Long-term efficacy and tolerability of the

Preclinical Pharmacokinetics, Pharmacodynamics and Safety of Sucroferric Oxyhydroxide
Article

Preclinical Pharmacokinetics, Pharmacodynamics and Safety of Sucroferric Oxyhydroxide

Abstract Sucroferric oxyhydroxide (VELPHORO) is a polynuclear iron-based phosphate binder recently approved for the treatment of hyperphosphataemia in patients

A phase III study of the efficacy and safety of a novel iron-based phosphate binder in dialysis patients
Article

A phase III study of the efficacy and safety of a novel iron-based phosphate binder in dialysis patients

Abstract Efficacy of PA21 (sucroferric oxyhydroxide), a novel calcium-free polynuclear iron(III)-oxyhydroxide phosphate binder, was compared with that of sevelamer carbonate in

The iron-based phosphate binder PA21 has potent phosphate binding capacity and minimal iron release across a physiological pH range in vitro
Article

The iron-based phosphate binder PA21 has potent phosphate binding capacity and minimal iron release across a physiological pH range in vitro

Abstract AIMS: Hyperphosphatemia in advanced chronic kidney disease (CKD) necessitates the use of phosphate binders. This in vitro study assessed phosphate binding and Fe release properties of the

PA21: a novel phosphate binder for the treatment of hyperphosphatemia in chronic kidney disease
Article

PA21: a novel phosphate binder for the treatment of hyperphosphatemia in chronic kidney disease

Abstract AIM: Limitations of conventional phosphate binders have led to the development of novel non-calcium, non-aluminium agents for use in patients with chronic kidney

Real-world effectiveness of sucroferric oxyhydroxide in patients on chronic hemodialysis: A retrospective analysis of pharmacy data
Article

Real-world effectiveness of sucroferric oxyhydroxide in patients on chronic hemodialysis: A retrospective analysis of pharmacy data

Abstract AIMS: Hyperphosphatemia has been associated with an increased risk of mortality in patients with end-stage renal disease. We sought to assess the

Iron-related parameters in dialysis patients treated with sucroferric oxyhydroxide
Article

Iron-related parameters in dialysis patients treated with sucroferric oxyhydroxide

Abstract Background Sucroferric oxyhydroxide is a non-calcium, iron-based

Pharmacodynamic Effects of Sucroferric Oxyhydroxide and Sevelamer Carbonate on Vitamin D Receptor Agonist Bioactivity in Dialysis Patients
Article

Pharmacodynamic Effects of Sucroferric Oxyhydroxide and Sevelamer Carbonate on Vitamin D Receptor Agonist Bioactivity in Dialysis Patients

Abstract BACKGROUND: Many patients with chronic kidney disease are prescribed vitamin D receptor agonists

Phosphate binders in chronic kidney disease: a systematic review of recent data
Article

Phosphate binders in chronic kidney disease: a systematic review of recent data

Abstract Hyperphosphatemia is common in chronic kidney disease

Improvement of mineral and bone metabolism markers is associated with better survival in haemodialysis patients: the COSMOS study
Article

Improvement of mineral and bone metabolism markers is associated with better survival in haemodialysis patients: the COSMOS study

Abstract BACKGROUND: Abnormalities in serum phosphorus, calcium and

Long-term effects of the iron-based phosphate binder, sucroferric oxyhydroxide, in dialysis patients
Article

Long-term effects of the iron-based phosphate binder, sucroferric oxyhydroxide, in dialysis patients

Abstract Background Hyperphosphatemia necessitates the use of phosphate

Preclinical Pharmacokinetics, Pharmacodynamics and Safety of Sucroferric Oxyhydroxide
Article

Preclinical Pharmacokinetics, Pharmacodynamics and Safety of Sucroferric Oxyhydroxide

Abstract Sucroferric oxyhydroxide (VELPHORO) is a polynuclear iron-based

A phase III study of the efficacy and safety of a novel iron-based phosphate binder in dialysis patients
Article

A phase III study of the efficacy and safety of a novel iron-based phosphate binder in dialysis patients

Abstract Efficacy of PA21 (sucroferric oxyhydroxide), a novel

The iron-based phosphate binder PA21 has potent phosphate binding capacity and minimal iron release across a physiological pH range in vitro
Article

The iron-based phosphate binder PA21 has potent phosphate binding capacity and minimal iron release across a physiological pH range in vitro

Abstract AIMS: Hyperphosphatemia in advanced chronic kidney disease

PA21: a novel phosphate binder for the treatment of hyperphosphatemia in chronic kidney disease
Article

PA21: a novel phosphate binder for the treatment of hyperphosphatemia in chronic kidney disease

Abstract AIM: Limitations of conventional phosphate binders have led to