Effect of Brexpiprazole on Prolactin and Sexual Functioning. An Analysis of Short- and Long-Term Study Data in Major Depressive Disorder

Purpose/Background

Evidence supports use of adjunctive atypical antipsychotics in major depressive disorder (MDD). Impaired sexual functioning is common in MDD and may be worsened by antipsychotic adverse effects. We evaluated the effect of brexpiprazole on prolactin and sexual functioning in patients with MDD.