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Abstract Background: Anxiety symptoms are common in patients with major depressive disorder (MDD) and usually confer worse treatment outcomes. The long-term,

Highlights • About 50% of MDD patients treated with SSRIs or SNRIs suffer emotional blunting • Emotional blunting has important functional consequences for patients’ daily life

Abstract Purpose Anhedonia is a core symptom of major depressive disorder (MDD), which has important functional consequences for the patient.

Abstract Objective: To assess changes in workplace productivity and functioning in an open-label study in working patients receiving vortioxetine (10 to

Abstract Objective: To evaluate the consistency of vortioxetine's effects on functional capacity in adults with major depressive disorder (MDD) and

Abstract Objective: AtWoRC (Assessment in Work productivity and the Relationship with Cognitive symptoms) was an interventional, open-label, Canadian study (NCT02332954) designed

Abstract Background: This analysis investigates the efficacy of vortioxetine in adults with major depressive disorder (MDD) who report childhood or recent

Abstract Background: Anhedonia is a common, persistent, and disabling phenomenon in treated adults with Major Depressive Disorder (MDD). Hitherto, relatively few

Abstract Background: Efficacy has been proven for vortioxetine in short-term and long-term treatment of major depressive disorder (MDD), with broad

Abstract Major depressive disorder is a common condition that often includes cognitive dysfunction. A systematic literature review of studies and