Highlights
- Depression and dementia are highly prevalent in older adults and often co-occur.
- Effectiveness of vortioxetine was assessed in patients with MDD and early-stage dementia.
- Significant improvement in depressive symptom severity after vortioxetine initiation.
- Cognitive performance significantly improved as assessed by the DSST and RAVLT.
- Daily and global functioning and quality of life also improved with vortioxetine.
Michael Cronquist Christensen, Simon Nitschky Schmidt, Iria Grande,
Effectiveness of vortioxetine in patients with major depressive disorder and early-stage dementia: The MEMORY study, Journal of Affective Disorders, Volume 338, 2023, Pages 423-431, ISSN 0165-0327,
https://doi.org/10.1016/j.jad.2023.06.024.